Immunosuppression Model

Nkag siab txog kev tiv thaiv kab mob thiab nws cov kev siv kho mob hauv kev tswj kev hloov pauv thiab kab mob autoimmune. Kawm txog Prisys 'cynomolgus liab qauv rau kev ntsuam xyuas cov teebmeem ntawm cov tshuaj tiv thaiv kab mob ntawm tib neeg lub cev, tshwj xeeb tshaj yog nyob rau hauv cov ntsiab lus ntawm psoriasis. Tshawb nrhiav qhov zoo ntawm kev siv cov qauv tsis yog tib neeg primate rau kev kho ua ntej kev kho mob tshiab.

Xa kev nug

Khoom Taw qhia

Kev tiv thaiv kab mob, qhov txo qis ntawm kev ua kom muaj zog lossis kev ua haujlwm ntawm lub cev tiv thaiv kab mob. Qee feem ntawm lub cev tiv thaiv kab mob nws tus kheej muaj kev tiv thaiv kab mob rau lwm qhov ntawm lub cev tiv thaiv kab mob, thiab kev tiv thaiv kab mob yuav tshwm sim raws li qhov tsis zoo rau kev kho mob ntawm lwm yam mob.Hauv Prisys, peb tau tsim kev tiv thaiv kab mob hauv cynomolgus liab.

Therapeutic Immunosuppression: Tswj kev hloov pauv thiab kab mob autoimmune

Feem ntau, txhob txwm tshaj tawm kev tiv thaiv kab mob yog ua los tiv thaiv lub cev los ntawm kev tsis lees txais kev hloov pauv hauv nruab nrog cev. Tsis tas li ntawd, nws yog siv los kho cov kab mob graft-tiv thaiv-tus tswv tsev tom qab hloov cov pob txha pob txha, lossis rau kev kho mob ntawm cov pob txha.auto-immune kab mob xws li systemic lupus erythematosus,mob caj dab rheumatoid , Sjögren's Syndrome, los yogCrohn tus kab mob . Qhov no feem ntau yog siv cov tshuaj, tab sis tej zaum yuav muaj kev phais (splenectomy), plasmapheresis, lossis hluav taws xob.

Qhov zoo ntawm NHP Immunosuppression qauv

Vim muaj qhov sib xws ntawm qhov sib txawv ntawm cov kab mob ntawm tib neeg thiab tsis yog tib neeg primate hom, cov qauv liab yog qhov muaj txiaj ntsig zoo tshaj plaws hauv kev ntsuam xyuas qhov cuam tshuam ntawm kev cuam tshuam rau tib neeg lub cev tiv thaiv kab mob.

Tus qauv Immunosuppression nyob rau hauv cynomolgus liab yog ib tug tsawg invasive thiab tsis-terminal qauv induced los ntawm cov tshuaj pleev ib ce.

Monkey Immunosuppression qauv yog qhov tseem ceeb hauv kev kho ua ntej kev txhim kho ntawm cov kab mob tshiab morbidity.