Nyob rau hauv niaj hnub biopharmaceutical R&D, tshwj xeeb tshaj yog rau cov kab mob hematological, vascular, thiab lub raum kab mob, kev xa tshuaj meej thiab tiag- lub sijhawm ntsuas kev taw qhia tau dhau los ua qhov tseem ceeb rau kev tsav cov tshuaj tshiab. Shanghai -raws liPrisys Biotech, nrog nwsDigital Subtraction Angiography (DSA)thiabIntraprocedural Sib Nqus Resonance Imaging (iMRI)technologies, ua ke nrog ib pab neeg muaj kev paub dhau los, tab tom hloov kho kev tshawb fawb preclinical, muab cov kev daws teeb meem tsis tau pom dua rau kev txhim kho tshuaj hauv cov kev nyuaj no.
Tiag -Lub Sijhawm Intraprocedural MRI (iMRI) Navigation: "X-Ray Vision" rau Precision Drug Delivery
Prisys Biotechtau txhim tsa Asia cov tho kevIntraprocedural MRI (iMRI) precision hlwb navigation thiab xa khoom. Qhov kev txiav-ntug thev naus laus zis no muab kev txhawb nqa zoo rau kev ncaj qha- rau- lub paj hlwb ntawm kev kho cov noob thiab lwm yam kev kho tshiab, ua kom cov tshuaj raug xa mus rau cov hom phiaj, yog li txhim kho cov txiaj ntsig kev kho mob thiab kev xa khoom tiav.
Core Advantages thiab Applications:
High -Kev xa khoom muaj tseeb:iMRI-cov thawj coj coj ua tiav sub-millimetric raug thiab raug. Piv txwv li, thaum kho Huntington's Disease (HD) nrog kev kho cov noob caj noob ces AMT-130, cov kws tshawb fawb tau siv iMRI kev taw qhia ncaj qha rau kev txhaj tshuaj rau hauv tus neeg mob lub putamen thiab caudate nucleus, ua rau qeeb qeeb ntawm cov kab mob. Qhov no ua piv txwv rau iMRI qhov tshwj xeeb muaj peev xwm hauv kev tsom mus rau cov kab mob neurological.
Bypassing ntshav-Brain Barrier (BBB):Cov thev naus laus zis no tso cai rau kev xa tshuaj ncaj qha thoob plaws BBB, ua kom muaj txiaj ntsig zoo ntawm cov tshuaj hauv zos thaum txo tag nrho cov tshuaj xav tau.
Tiag -Sim Optimization thiab Visualization:Cov txheej txheem xa tshuaj mus rau lub hlwb tuaj yeem pom hauv lub sijhawm tiag tiag -, tso cai rau kev ua kom zoo dua ntawm cov txheej txheem nkag mus rau lub hlwb.Prisys Biotech Covlub kaw lus tseem tuaj yeem tsim cov ntaub ntawv tiag tiag - lub sijhawm them cov ntaub ntawv ntawm lub hom phiaj hauv cheeb tsam lub paj hlwb tom qab - txhaj tshuaj.
Txhim Kho Tshuaj Distribution:Ua ke nrogConvection -Kev xa khoom zoo (CED), iMRI kev taw qhia ua tau zoo txhim kho kev faib tawm ntawm micro-dosed tshuaj nyob rau hauv lub hom phiaj cov qauv, ntxiv kev txhim kho cov txiaj ntsig kho.
Seamless Clinical Txhais Lus: Prisys Biotech CoviMRI system siv tib lub thev naus laus zis thiab cov cuab yeej siv raws li kev ua haujlwm hauv kev sim tshuaj, kom ntseeg tau tias cov ntaub ntawv tshawb fawb ua ntej tuaj yeem txhais tau zoo rau hauv kev siv tshuaj kho mob. Qhov no yog qhov tseem ceeb rau kev txhim kho ntau yam tshuaj, suav nrog cov molecules me, biologics, cell thiab noob kev kho mob, nanoparticles, thiab nucleic acid kho.
Prisys Biotechtau koom tes nrog ntau lub tuam txhab tshuaj loj hauv kev tshawb fawb tshawb fawb txog biodistribution thiab qhia txog kev kho noob hauv lub hlwb ntawm cov tsis yog -tib neeg primates (NHPs), siv iMRI-cov tswv yim qhia kom meej xa AAV9 noob kev kho rau striatum (putamen.) rau kev ntsuas
Digital Subtraction Angiography (DSA): Cov cuab yeej muaj zog rau kev cuam tshuam vascular thiab ntau yam -Lub cev xa mus
DSA thev naus laus zis yog lwm lub peev xwm tseem ceeb ntawmPrisys Biotechhauv kev tshawb fawb ntawm hematological, vascular, thiab lwm yam kab mob. Nws muab siab - daws teeb meem vascular imaging, ua kom muaj kev cuam tshuam vascular tsawg tsawg thiab ua kom muaj kev tswj hwm cov tshuaj thiab tso catheter.
Dav -Kev siv ntau yam:
Kab mob Modeling nyob rau hauv hematology thiab Vascular mob:DSA ua lub luag haujlwm tseem ceeb hauv kev tsim cov qauv kab mob. Piv txwv li,Prisys Biotechtau ntse tsim ib qhoischemic stroke (Middle Cerebral Artery Occlusion, MCAO) qauv hauv cynomolgus liablos ntawm kev siv DSA kev taw qhia los qhia ib qho autologous thrombus mus rau hauv nruab nrab cerebral hlab ntsha ntawm lub femoral artery catheter. Txoj kev no ua tib zoo ua tib neeg mob stroke pathology nrog qhov zoo xws li kev raug mob me me, muaj teeb meem tsawg dua, kev rov tsim dua tshiab, thiab yooj yim ntawm kev ntsuas ntau.
Ntau -Lub Hom Phiaj Xa Khoom:DSA thev naus laus zis pab txhawb kev xa mus rau ntau lub cev, suav nrog ureterography thiab lub hom phiaj ntawm lub cev perfusion hauv lub raum kev tshawb fawb. Qhov no yog qhov tseem ceeb rau hauv - kev tshawb fawb tob rau hauv cov kab mob hauv lub raum mechanisms thiab ntsuam xyuas hauv -vivo kev ua tau zoo ntawm cov tshuaj tshiab rau lub raum.
Kev cuam tshuam ntawm Cardiovascular thiab Neurovascular Interventions: Prisys Biotech CovDSA suite tuaj yeem siv rau ntau yam kev cuam tshuam, suav nrog cov hlab plawv, cerebrovascular, thiab peripheral vascular interventions. Nws tuaj yeem ua ke nrog chav ua haujlwm huv los tsim "chav ua haujlwm hybrid," ua kom muaj kev sib koom ua ke ntawm kev cuam tshuam me me nrog cov txheej txheem phais ib txwm los daws cov teeb meem phais nyuaj.
Pharmacokinetic (PK) Kev Kawm:DSA- pab tsim kom muaj cov vascular nkag tau yooj yim kuj txhawb cov kev tshawb fawb pharmacokinetic. Piv txwv li, hauv kev koom tes nrog ib tus kws kho mob, kev kuaj ntshav los ntawm DSA- qhia catheterization tau siv los ntsuas kev hloov tshuaj concentration hauv vivo.
Prisys Biotech CovDSA platform nta validated guidewires thiab catheters haum rau minimally invasive xa mus rau ntau yam kabmob. Tsis tas li ntawd,Prisys Biotechboasts ib pab neeg paub txog ntawm kev cuam tshuam hluav taws xob, ua kom txhua tus txheej txheem ua raws li cov txheej txheem kho mob siab tshaj plaws.
Comprehensive Imaging Platform: Holistic, Siab -Vimage Translational Assessment
Prisys Biotech Covkev kho mob imaging platformNws txuas ntxiv dhau ntawm iMRI thiab DSA, kev sib koom ua ke CT scanning, Doppler ultrasound, endoscopy, thiab lwm yam kev kuaj xyuas cov qauv. Ua ke, cov cuab yeej no tsim ib qho kev ntsuam xyuas kev ntsuam xyuas, muab ntau yam - cov ntaub ntawv rau kev txhim kho tshuaj tshiab.
CT Scanning:Dav siv rau kev tshuaj ntsuam xyuas thoob plaws ntau lub cev (tsis suav nrog cov kab mob plawv), suav nrog kev tshuaj xyuas lub ntsws nodule, emphysema quantification, thiab cranial perfusion tsom. Nws kuj tuaj yeem pab taunaso-cerebral (N2B) kev xa tshuajkev tshawb fawb los ntawm kev pom cov tshuaj tso rau hauv qhov ntswg kab noj hniav.
Kev taw qhia Ultrasound:Ua hauj lwm rau lub lumbar puncture thiab intrathecal nkag, txhawb cerebrospinal kua (CSF) sau thiab tshuaj noj.
Kev txhais cov ntaub ntawv: Prisys Biotech Covpab pawg kws tshuaj ntsuam xyuas suav nrog cov kws kho mob yav dhau los uas muaj kev paub dhau los hauv tib neeg kev tshuaj ntsuam xyuas thiab tshuaj ntsuam xyuas, kom ntseeg tau tias cov ntaub ntawv tsiaj cov qauv tuaj yeem raug muab ncaj qha rau tib neeg cov xwm txheej kho mob, ua tiav qhov kev kwv yees siab thiab kev tshuaj ntsuam xyuas.
Preclinical Innovation nrog Precision Imaging
Nrog nws cov kev txawj ntse thiab kev siv cov kev paub hauv kev cuam tshuam thiab cov duab navigation technologies zoo li iMRI thiab DSA,Prisys Biotechmuab cov kev hloov kho preclinical kev daws teeb meem rau kev txhim kho tshuaj tsom rau cov xwm txheej nyuaj xws li hematological, vascular, thiab raum kab mob. Peb mob siab rau ua kom cov txheej txheem tsim tshuaj tshiab rau peb cov neeg koom tes biopharmaceutical thoob ntiaj teb los ntawm peb cov kev txiav- cov txheej txheem thev naus laus zis, pab pawg kws tshaj lij, thiab kev tswj hwm tsiaj txhu zoo uas ua tau raws li cov qauv thoob ntiaj teb (cov pov thawj los ntawm peb daim ntawv lees paub AAALAC), thaum kawg txhawm rau txhim kho tib neeg kev noj qab haus huv.
Hu rau Prisys Biotech niaj hnub no kom paub ntau ntxiv txog peb lub peev xwm hauv kev cuam tshuam thiab cov duab navigation thiab sib tham txog yuav ua li cas peb tuaj yeem pab txhawb koj cov phiaj xwm tshiab tshuaj.
