Xauv tag nrho cov peev xwm ntawm cov tshuaj nucleic acid nthuav tawm qhov kev txaus siab nyob rau hauv kev kho tshiab, nrog kev cog lus ntawm kev kho mob ntau yam xws li mob qog noj ntshav, kab mob kis kab mob, thiab kab mob caj ces. Txawm hais tias lawv muaj ntau qhov zoo, cov kev cov nyom tseem muaj nyob rau hauv kev tsim cov tshuaj nucleic acid, tshwj xeeb tshaj yog nyob rau hauv kev ruaj ntseg, kev xa khoom, kev tiv thaiv kab mob, thiab kev ua tau zoo.
Prisys Biotech sawv ntawm qhov ua ntej ntawm kev kov yeej cov kev cov nyom no, tshwj xeeb hauv Nonhuman Primate (NHP) qauv los txhawb kev tshawb fawb thiab kev tsim tshuaj nucleic acid. Prisys kev cog lus txuas ntxiv mus hais txog cov teeb meem tseem ceeb, suav nrog kev ruaj ntseg, kev xa khoom, kev tiv thaiv kab mob, thiab lub hom phiaj zoo.
NHP kev tshawb fawb platform ntawm Prisys ua tus tshiab ntawm nucleic acid kho:
1. Xeev-ntawm-the-art NHP Research Facility:
Prisys Pharma-scale,AAALAC-kev lees paub qhov chawnyob rau hauv Shanghai, Tuam Tshoj, yog ib qhov loj tshaj plaws thiab siab tshaj plaws NHP kev tshawb fawb chaw nyob rau hauv lub ntiaj teb no. Peb txhawb nqa cov qauv siab tshaj plaws ntawm kev noj qab haus huv tsiaj thiab kev tshawb fawb zoo, ua raws li cov lus qhia thoob ntiaj teb thiab cov cai. Prisys chaw muaj ntau tshaj 400 NHP lub peev xwm vaj tse, kev kuaj pom thiab cov kab hluav taws xob, hauv vitro bioanalysis muaj peev xwm, thiab pab pawg neeg muaj kev paub txog kws kho tsiaj thiab cov kws tshawb fawb.
2. Tshwj xeeb Sourced NHP Breeding Colony:
Peb tuav ib qho tshwj xeeb ntawm NHP yug me nyuam colony, Cynomolgus macaques. Prisys colony yog cov noob caj noob ces thiab phenotypically tus yam ntxwv, ua kom tus nqi - zoo thoob ntiaj teb NA tus neeg sib tw xaiv thiab txo cov kev pheej hmoo ntawm kev tsis sib haum xeeb. Peb kuj muab kev pabcuam yug me nyuam thiab genotyping raws li cov kev xav tau tshwj xeeb ntawm cov neeg siv khoom Prisys.
3. Kws tshaj lij hauv NA Kev Xa Tshuaj:
Prisys cov kev paub tshwj xeeb suav nrog ntau txoj hauv kev ntawm NA kev xa tshuaj hauv NHP, tsom rau ob lub siab thiab tsis yog - cov kab mob siab rau ntau yam kab mob thiab cov qauv tsim. Peb muaj kev txawj ntse hauv RNAi kws tshuaj, xws li intrahepatic thiab extrahepatic xa technologies, chaw kho mob endpoints, thiab immunogenicity/allergy ntsuam xyuas. Peb kuj muaj kev paub txog kev xa lwm yam tshuaj me me nucleic acid, xws li antisense oligonucleotides, aptamers, thiab DNAzymes.
4. Kev txawj ntse hauv NHP Hauv -Kev Sau Npe Lub Neej:
Prisys ua tau zoo hauv kev txheeb xyuas biomarker, muab cov ntaub ntawv raug los txhawb cov neeg siv khoom hauv kev nkag siab cov tshuaj nucleic acid lub hom phiaj qhia. Peb muab ntau txoj hauv kev kuaj cov qauv sau, suav nrog cov qauv nyob thiab ntau-cov khoom siv hauv nruab nrog cev. Peb qhov kev txawj ntse suav nrog cov txheej txheem xws li daim siab biopsy, raum biopsy, ntsws biopsy, kua chromatography-mass spectrometry, quantitative PCR, thiab ELISA. Nrog rau cov tswv yim no, peb ntsuas cov tshuaj pharmacokinetics, pharmacodynamics, thiab kev nyab xeeb ntawm cov tshuaj nucleic acid hauv Non-Human Primates (NHP). Peb qhov tseeb thiab dav biomarker tsom xam ua kom paub txog kev txiav txim siab- ua thaum lub sijhawm tsim tshuaj, txhawb cov kws tshawb fawb los txhawb lawv qhov kev tshawb pom hauv thaj chaw tshuaj nucleic acid.
5. Cov Qauv Kab Mob NHP nrog Cov Kev Kho Mob Kawg:
Prisys NHP kab mob qauv, nruab nrog cov chaw kho mob kawg, txhais ncaj qha rau kev sim tshuaj. Kev siv tib neeg cov qauv ntawm cov duab zoo tshaj plaws, cov txheej txheem txhaj tshuaj, thiab kev ntsuas kev soj ntsuam, peb muab cov kev pom tseeb rau kev txhim kho tshuaj. Peb muab ntau hom kab mob NHP rau ntau yam kev kho mob, xws li kev tiv thaiv kab mob, kab mob siab, kab mob, ophthalmology, hematology, nephrology, cardiovascular, metabolism, ua pa, neurology, thiab oncology. Peb kuj muaj cib fim rau kev sib koom ua ke- txhim kho cov qauv NHP tshiab nrog cov neeg siv khoom Prisys.
Los ntawm kev siv Prisys NHP kev tshawb fawb platform, koj tuaj yeem tau txais txiaj ntsig los ntawm Prisys cov txiaj ntsig tshwj xeeb, xws li:
-High-NHP cov peev txheej thiab cov chaw zoo
-Txiav-ntug NA tshuaj xa thiab tshuaj xyuas technologies
-Piv tauNHP kab mob qauvthiab cov ntsiab lus kawg
-Txoj kev tshawb fawb txog kev ntseeg siab thiab ncaj ncees
-Cov qauv sib koom ua ke yooj yim thiab sib koom ua ke
Qhov deb - ncav cuag lub peev xwm ntawm cov tshuaj nucleic acid yog qhov zoo- tsim, nthuav tawm lub peev xwm uas tsis muaj peev xwm los daws ntau yam kab mob nyuaj uas tsis sib piv nrog lwm hom tshuaj. Prisys 'Tsis yog -Human Primate (NHP) kev tshawb fawb platform, cov cuab yeej muaj zog no hais txog cov teeb meem nyuaj hauv kev tshawb fawb thiab kev tsim cov tshuaj nucleic acid, ua kom cov kev hloov pauv ntawm cov tswv yim tshiab los ntawm cov chaw kuaj mob mus rau kev kho mob.
Peb ua tsaug caw koj mus cuag Prisys Biotech. Tau txais kev nkag siab txog yuav ua li cas peb lub NHP kev tshawb fawb platform tuaj yeem ua lub cuab tam muaj txiaj ntsig, ntxiv tus nqi tshwj xeeb rau koj cov txheej txheem tsim tshuaj nucleic acid, thiab txhawb kev hloov pauv ntawm koj cov kev txiav - ntug kev tsim kho tshiab.
