Hauv cov toj roob hauv pes hloov zuj zus ntawm kev tshawb fawb thiab kev loj hlob ntawm cov tshuaj, qhov kev xav tau ntawm kev txhim khu kev qha thiab tshiab preclinical platforms yeej tsis tau ntau dua. Prisys Biotechnologies sawv ntawm qhov ua ntej ntawm daim teb no, muab cov khoom tshwj xeeb uas tsis yog - tib neeg primate (NHP, Cynomolgus macaques) ua qauv rau kev kawm hauv kev tiv thaiv kab mob thiab mob (I&I). Peb lub hom phiaj yog los pab txhawb kev hloov pauv tshuaj R&D rau ntau yam I & I qhia los ntawm cov txheej txheem dav thiab muaj zog.
Unmatched Expertise nyob rau hauv Immunology thiab Inflamation Models
Ntawm Prisys Biotechnologies, peb txaus siab rau peb tus kheej ntawm peb qhov kev paub dhau los thiab ua pov thawj ua tiav hauv thaj av ntawm NHP cov kev tshawb fawb. Peb lub peev xwm suav nrog ntau yam ntawm I & I qauv, tsim kom zoo zoo los txhawb kev txhim kho thiab hloov pauv ntawm ntau hom tshuaj. Nov yog saib ze dua ntawm peb cov khoom:
Comprehensive I & Kuv Models
Peb cov ntaub ntawv muaj xws li cov qauv rau ntau yam kab mob I&I xws li:
- NHP Kab Mob Models: Tsis yog -tib neeg primates (NHPs) yog hom zoo tshaj plaws rau kev tshawb fawb txog kev tiv thaiv kab mob vim lawv cov caj ces ze thiab kev tiv thaiv kab mob zoo sib xws rau tib neeg.
- Rheumatoid mob caj dab (RA): Tus qauv RA siv cov cynomolgus liab thiab suav nrog kev txhim kho induction raws tu qauv rau cov xwm txheej siab, nrog CRP ua cov cuab yeej kwv yees rau RA pib.
- Psoriasis thiab Atopic Disease: Cov qauv rau psoriasis thiab cov kab mob atopic zoo ib yam li mob hawb pob thiab ua xua rhinitis yog tsim los siv OVA (ovalbumin) cov kev cov nyom thiab cov yam ntxwv ntawm daim tawv nqaij thiab lub ntsws kev ua haujlwm.
- ncua -hom Hypersensitivity (DTH): Cov qauv no siv Tetanus toxin los ua kom muaj qhov mob DTH cov tshuaj tiv thaiv, nrog rau cov lus teb rov qab los ntawm kev sib tw dua. Nws muaj txiaj ntsig zoo rau kev ntsuas kev ua tau zoo, immunogenicity, thiab immunotoxicity.
- T cell{0}}dependent Antibody Response (TDAR): Qhov kev ntsuam xyuas TDAR, suav nrog Keyhole Limpet Hemocyanin, yog tus qauv rau kev ntsuas qhov cuam tshuam ntawm cov tshuaj ntawm kev tiv thaiv kab mob, suav nrog kev siv tshuaj tiv thaiv kab mob, T cell pab, B cell activation, thiab kev tsim tshuaj tiv thaiv kab mob.
- Cov qauv no yog crafted los ua raws li txoj kev nyuaj pathophysiology ntawm tib neeg tej yam kev mob, muab invaluable invaluable kev pom rau cov kab mob mechanisms thiab kho tau zoo.
Versatile Support rau ntau yam tshuaj Modality
Prisys Biotechnologies muaj cov ntaub ntawv nplua nuj ntawm kev soj ntsuam zoo thiab hloov cov tshuaj hloov pauv, xws li cov khoom me me mus rau biologics, thiab los ntawm cov tshuaj tiv thaiv mus rau kev kho noob. Peb txoj hauv kev ua kom paub tseeb tias koj cov txheej txheem kev txhim kho tshuaj tau txais kev txhawb nqa los ntawm cov ntaub ntawv preclinical robust.
Kev hloov kho kho mob nrog Advanced Techniques
Txhawm rau txuas qhov sib txawv ntawm kev tshawb fawb txog kev kho mob thiab kev kho mob, peb muab kev hloov pauv hauv vivo imaging thiab bio-sampling cov phiaj xwm. Cov peev txheej no tso cai rau kev taug qab meej txog kev tiv thaiv kab mob thiab mob ntev thiab hloov pauv kab mob, ua kom yooj yim rau kev txhais lus kho mob.
Immunology Assay
Peb cov tshuaj tiv thaiv kab mob rau cov kev tshawb fawb NHP tsis yog qhov thib ob. Peb muab cov ncauj lus kom ntxaws tsom xam ntawm:
- Ntshav Immunoglobulins (IGs):kev siv ntawmNws pib Hematology AnalyzerthiabBiochemistry Analyzeruas tuaj yeem siv rau kev kuaj ntshav biochemical indices, uas tuaj yeem suav nrog immunoglobulins.
- Immunocyte Panels:kev siv ntawmFlow Cytometrynrog ntau qhov ntsuas xws li CD3, CD4, CD8, thiab lwm yam rau kev tiv thaiv kab mob B hlwb, T hlwb, monocytes, myeloid, NK hlwb, thiab ntau dua.
- Cytokine Profiles:CovTxhim kho Bioanalysis platformsuav nrog cov thev naus laus zis xws li LC-MS, Chemiluminescence, thiabELISA tsom xam qhov systemuas feem ntau yog siv los txheeb xyuas cytokine profiles.
- Cov kev ntsuam xyuas no yog qhov tseem ceeb rau kev nkag siab txog kev tiv thaiv kab mob ntawm koj cov neeg sib tw kho mob.
Kev sib koom tes thiab kev nug
Peb tau cog lus rau kev txhawb nqa kev sib koom tes ntawm kev sib koom tes uas txhawb nqa kev tsim kho tshiab thiab kev vam meej hauv kev tsim tshuaj. Yog tias koj txaus siab tshawb nrhiav peb cov qauv NHP lossis npaj ib qho kev nthuav qhia hauv online, thov tsis txhob yig tiv tauj. Peb pab neeg npaj txhij los pab koj ua tiav koj cov hom phiaj tshawb fawb.
Hais txog Prisys Biotechnologies
Prisys Biotechnologies yog tus muab kev pabcuam ntawm NHP kev kawm muaj peev xwm, mob siab rau kev nce qib kev tiv thaiv kab mob thiab kev tshawb fawb mob. Peb cov txheej txheem preclinical tshiab yog tsim los txhawb cov tiam tom ntej ntawm kev kho kom zoo. Nrog rau kev tsom mus rau kev ua tau zoo thiab kev sib koom tes, peb yog koj tus khub ntseeg siab hauv kev tsim tshuaj.Yog xav paub ntxiv thiab nug txog peb cov kev pabcuam, thov hu rau peb hnub no. Ua ke, peb tuaj yeem hloov kho toj roob hauv pes ntawm kev tiv thaiv kab mob thiab kev tshawb fawb mob.
Ntsiab lus
Tsis yog -tib neeg cov qauv primate
Cov qauv kev mob caj dab Rheumatoid
Ntau yam Sclerosis qauv
Cov kab mob plab hnyuv kab mob
Lub cev -kev mob tshwj xeeb
Bio-sampling
Immunology kev soj ntsuam
Ntshav immunoglobulins
Immunocyte panels
Cytokine profiles
